Description

Mycophenolic Acid o-Desmethyl Ether is a key pharmaceutical intermediate and metabolite of interest. This compound is valued for its role in the development and quality control of immunosuppressive therapies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for analytical reference standards, impurity profiling, and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of advanced immunosuppressant drugs.
• Analytical Reference Standard: Used in HPLC, LC-MS, and other chromatographic methods for method development, validation, and quantification.
• Metabolite Studies: Employed in pharmacokinetic and pharmacodynamic research to study drug metabolism pathways.
• Impurity Standard: Serves as a certified reference material for identifying and controlling process-related impurities in finished drug products.
• Biochemical Research: Used as a tool compound in in-vitro studies to investigate mechanisms of action related to inosine monophosphate dehydrogenase (IMPDH) inhibition.
• Quality Control (QC) & Quality Assurance (QA): Essential for ensuring batch-to-batch consistency and compliance with regulatory specifications in API manufacturing.

Basic Information

Product Name	Mycophenolic Acid o-Desmethyl Ether
CAS No.	24243-36-5
Molecular Formula	C16H18O6
Molecular Weight	306.31 g/mol
Synonyms	6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid; 7-O-Methylmycophenolic Acid; o-Desmethyl Mycophenolic Acid; 7-O-Methyl-MPA; MPA 7-O-Methyl Ether; Mycophenolic Acid 7-Methyl Ether; 24243-36-5; 5-(4-Methyl-1-oxo-4-pentenyl)-4-methoxy-6-methyl-7-hydroxyphthalide
EINECS	Contact for details

Quality Control

Our Mycophenolic Acid o-Desmethyl Ether is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.