Description

(S)-5-Hydroxy-Piperidin-2-One CAS NO 24211-54-9 is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. Its value lies in its stereochemically defined hydroxylated lactam structure, which is a key motif for constructing complex molecules with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts in stereoselective transformations.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and protease inhibitors due to its lactam scaffold.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(S)-5-Hydroxy-Piperidin-2-One
CAS No.	24211-54-9
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	(S)-5-Hydroxypiperidin-2-one; (5S)-5-Hydroxypiperidin-2-one; (S)-5-Hydroxy-2-piperidinone; L-5-Hydroxypiperidin-2-one; (S)-5-Hydroxy-δ-valerolactam; 5-Hydroxy-2-piperidinone, (S)-; (S)-5-Hydroxy-2-piperidone; (S)-5-Hydroxypiperidinone
EINECS	Contact for details

Quality Control

Every batch of (S)-5-Hydroxy-Piperidin-2-One is produced under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the highest standards. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data for chiral purity (HPLC), assay, and related substances. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.