Description

2-Piperazinone, Hydrochloride is a high-purity organic salt of significant importance in advanced chemical synthesis. This compound serves as a versatile and critical building block for the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for their synthetic processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those containing piperazine or morpholine-like heterocyclic structures.
• API Synthesis: Used in the manufacturing of Active Pharmaceutical Ingredients (APIs) for central nervous system (CNS) agents, antimicrobials, and other therapeutic classes.
• Agrochemical Research: Serves as a building block for developing novel pesticides, herbicides, and plant growth regulators.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating novel chemical entities.
• Ligand and Catalyst Preparation: Useful in the preparation of specialized ligands for metal catalysis and asymmetric synthesis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	2-Piperazinone, Hydrochloride
CAS No.	24123-06-6
Molecular Formula	C4H8N2O·HCl
Molecular Weight	136.58 g/mol
Synonyms	2-Ketopiperazine Hydrochloride; Piperazin-2-one Hydrochloride; 2-Oxopiperazine Hydrochloride; Diketopiperazine Hydrochloride; Aminoethylglycine Ketone Hydrochloride; 1,4-Diazinan-2-one Hydrochloride; Cyclo(glycyl-ethylene imine) Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Piperazinone, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.