Description

2-(2-Fluorobenzyl)Acetoacetic Acid Ethyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound matters as a versatile intermediate, enabling the precise introduction of a fluorobenzyl moiety into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in fluorination chemistry and cross-coupling reactions.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing complex fluorinated ligands used in asymmetric catalysis.

Basic Information

Product Name	2-(2-Fluorobenzyl)Acetoacetic Acid Ethyl Ester
CAS No.	24106-86-3
Molecular Formula	C₁₃H₁₅FO₃
Molecular Weight	238.26 g/mol
Synonyms	Ethyl 2-(2-Fluorobenzyl)-3-oxobutanoate; Ethyl (2-Fluorobenzyl)acetoacetate; 3-Oxobutanoic acid, 2-[(2-fluorophenyl)methyl]-, ethyl ester; Acetoacetic acid, 2-(2-fluorobenzyl)-, ethyl ester; 2-(2-Fluorobenzyl)acetoacetate ethyl ester; Ethyl 2-(o-fluorobenzyl)acetoacetate; 24106-86-3; Ethyl 2-(2-fluorobenzyl)-3-oxobutyrate
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorobenzyl)Acetoacetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The container must be kept tightly closed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.