Description

Glutamic Acid, L-, [5-14C] is a carbon-14 labeled isotopologue of the essential amino acid L-Glutamic acid, specifically radiolabeled at the 5-carbon position. This product is critical for conducting precise metabolic and pharmacokinetic tracer studies, enabling researchers to track the compound's pathway and fate in biological systems. It is an indispensable tool for scientists in pharmaceutical R&D, biochemistry, and metabolic research who require high-specific-activity radiochemicals for advanced analytical applications.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the biosynthesis and catabolism of glutamic acid and related compounds like glutamine and GABA in vivo and in vitro.
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for ADME (Absorption, Distribution, Metabolism, Excretion) studies of new pharmaceutical compounds that interact with glutamatergic pathways.
• Biochemical Research: Investigates enzyme kinetics, protein synthesis, and nitrogen metabolism in plants, animals, and microorganisms.
• Neuroscience Studies: Applied in research on excitatory neurotransmission, synaptic plasticity, and neurological disorders.
• Agricultural Chemistry: Used in studies of amino acid uptake and metabolism in crops.
• Quality Control Reference: Serves as an internal standard in advanced analytical techniques such as LC-MS for accurate quantification.

Basic Information

Product Name	Glutamic Acid, L-, [5-14C]
CAS No.	24016-48-6
Molecular Formula	C5H914CNO4
Molecular Weight	Contact for details
Synonyms	(2S)-2-Aminopentanedioic-5-14C acid; L-Glutamic-5-14C acid; (S)-2-Aminopentanedioic-5-14C acid; L-Glu-5-14C; Glutamic Acid-5-14C; [5-14C]-L-Glutamic Acid; 5-14C-L-Glutamate; 2-Aminoglutaric-5-14C acid
EINECS	Contact for details

Quality Control

Every batch of our Glutamic Acid, L-, [5-14C] is manufactured and analyzed under strict quality systems to ensure high chemical, radiochemical, and enantiomeric purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific activity, purity by HPLC, radiochemical purity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is hygroscopic (moisture-sensitive). Allow the vial to reach ambient temperature before opening to minimize moisture intake. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details
Chiral Purity (HPLC)	≥ 99% (L-isomer)
Solvent (for solution forms)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.