Description

R(+)-Sulpiride is the pharmacologically active enantiomer of the substituted benzamide derivative Sulpiride. This high-purity chiral compound is critical for research and development in neuropharmacology, serving as a selective dopamine D2 and D3 receptor antagonist. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced neuropsychiatric research.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control of Sulpiride-based drug products.
• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of enantiomerically pure neuroleptic and antipsychotic medications.
• Neuroscience Research: Employed in preclinical studies to investigate the specific roles of dopamine receptor subtypes in behavior, psychosis, and mood disorders.
• Metabolite Studies: Used in the synthesis and identification of metabolic pathways for Sulpiride in pharmacokinetic and ADME (Absorption, Distribution, Metabolism, Excretion) research.
• Asymmetric Synthesis: Serves as a model compound or intermediate in developing and optimizing chiral separation techniques and asymmetric synthetic routes.

Basic Information

Product Name	R(+)-Sulpiride
CAS No.	23756-79-8
Molecular Formula	C15H23N3O4S
Molecular Weight	341.42 g/mol
Synonyms	(R)-(+)-Sulpiride; Dextro-Sulpiride; (+)-Sulpiride; (R)-Sulpiride; (R)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide; (R)-5-(Ethylsulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide; R(+)-Sulpiride; (R)-Sulpirid
EINECS	Contact for details

Quality Control

Our R(+)-Sulpiride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (R-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.