Description

5-(Aminosulphonyl)-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxybenzamide Monohydrochloride is a high-purity pharmaceutical intermediate and active ingredient salt with significant importance in modern medicinal chemistry. This compound is valued for its role as a key building block in the synthesis of complex therapeutic agents, particularly those targeting the central nervous system. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of advanced drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel therapeutic compounds, especially in neurological and psychiatric drug research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and development of new chemical entities (NCEs) where its structural motif is integral to biological activity.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Biochemical Research: Utilized in pharmacological studies to investigate receptor binding affinities and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: A key material for process optimization and pilot-scale production runs in cGMP manufacturing environments.
• Academic Research: Used in university and institutional labs for advanced organic synthesis projects and medicinal chemistry programs.

Basic Information

Product Name	5-(Aminosulphonyl)-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxybenzamide Monohydrochloride
CAS No.	23694-14-6
Molecular Formula	C15H24N4O4S • HCl
Molecular Weight	400.90 g/mol
Synonyms	Sultopride Hydrochloride; Barnetil; Barnotyl; Topral; 2-Methoxy-5-sulfamoyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide Hydrochloride; 5-Sulfamoyl-o-anisamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-, monohydrochloride; Sultopride HCl; CL-71563
EINECS	Contact for details

Quality Control

Our 5-(Aminosulphonyl)-n-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxybenzamide Monohydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and conformity to stringent specifications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation. The original container should be kept sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.