Description

Naphthalene, 2-(Bromomethyl)-1-Fluoro- is a halogenated naphthalene derivative that serves as a versatile and high-value fluorinated building block in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials for displays and lighting applications.
• Polymer Modification: Employed to introduce fluorinated and reactive bromomethyl groups into polymer backbones, altering physical and chemical properties.
• Cross-Coupling Reactions: The bromomethyl group acts as a handle for further functionalization via Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Useful for synthesizing specialized fluorinated ligands for catalysis and molecular recognition.

Basic Information

Product Name	Naphthalene, 2-(Bromomethyl)-1-Fluoro-
CAS No.	23683-25-2
Molecular Formula	C₁₁H₈BrF
Molecular Weight	239.09 g/mol
Synonyms	1-Fluoro-2-(bromomethyl)naphthalene; 2-(Bromomethyl)-1-fluoronaphthalene; 1-Fluoro-2-bromomethylnaphthalene; (2-Bromomethyl)-1-fluoronaphthalene; Naphthalene, 1-fluoro-2-(bromomethyl)-; 23683-25-2; 2-Bromomethyl-1-fluoronaphthalene
EINECS	Contact for details

Quality Control

Our Naphthalene, 2-(Bromomethyl)-1-Fluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.