Description

Bpoc-Ala-Oh CAS NO 23631-89-2 is a specialized N-protected amino acid derivative, where the α-amino group of alanine is blocked by the 2-(4-biphenylyl)-2-propyloxycarbonyl (Bpoc) protecting group. This compound is critical for advanced peptide synthesis, offering superior acid-lability for selective deprotection strategies under mild conditions. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for creating complex peptide-based therapeutics and novel drug candidates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptides, especially in Fmoc/t-Bu strategies where orthogonal protection is required.
• Pharmaceutical Research & Development: Used in the synthesis of peptide APIs (Active Pharmaceutical Ingredients) and investigational new drugs for various therapeutic areas.
• Bioconjugation and Peptide Labeling: Serves as a precursor for creating modified peptides with tags, probes, or linkers for diagnostic and biochemical studies.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Academic and Industrial Research: A fundamental reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Bpoc-Ala-Oh
CAS No.	23631-89-2
Molecular Formula	C₁₉H₂₁NO₄
Molecular Weight	327.37 g/mol
Synonyms	2-(4-Biphenylyl)-2-propyloxycarbonyl-L-alanine; (S)-2-((2-(4-Biphenylyl)propan-2-yl)oxycarbonylamino)propanoic acid; Bpoc-L-alanine; Bpoc-Ala-OH; N-[(2-(4-Biphenylyl)propan-2-yl)oxycarbonyl]-L-alanine; N-Bpoc-L-alanine; L-Alanine, N-[(2-(4-biphenylyl)-2-propoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Every batch of Bpoc-Ala-Oh is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive peptide synthesis. A Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), chiral purity, and impurity profiles is available for each lot upon request, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.