Description

3-(Trifluoromethyl)Cyclohexanamine is a versatile fluorinated amine building block, valued for its unique combination of a cyclohexyl backbone and a trifluoromethyl group, which imparts desirable properties like enhanced lipophilicity and metabolic stability. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where the introduction of fluorine atoms is a key strategy for optimizing biological activity. It serves as a critical raw material for researchers and manufacturers in the life sciences and specialty chemical sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances efficacy and environmental profile.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor for fluorinated compounds used in liquid crystal displays (LCDs) and other electronic materials.
• Organic Synthesis & Catalysis: Employed as a ligand or building block in asymmetric synthesis and the development of novel catalysts.
• Material Science Research: Utilized in the creation of specialty polymers and coatings with specific surface properties and chemical resistance.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclohexanamine
CAS No.	23566-61-2
Molecular Formula	C7H12F3N
Molecular Weight	167.17 g/mol
Synonyms	3-(Trifluoromethyl)cyclohexanamine; 3-(Trifluoromethyl)cyclohexylamine; 3-Trifluoromethylcyclohexanamine; Cyclohexanamine, 3-(trifluoromethyl)-; α,α,α-Trifluoro-m-toluidine, hexahydro-; 3-(Trifluoromethyl)-1-cyclohexanamine
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Cyclohexanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key specifications are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.