Description

Methanesulfonamide, 1,1,1-Trifluoro-n-(3-Fluorophenyl)- is a specialized fluorinated sulfonamide derivative, identified by CAS NO 23384-01-2, valued for its unique trifluoromethyl and aryl fluoride substituents which impart distinct electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in modern synthetic chemistry. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the stability of the trifluoromethyl group.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and other advanced materials requiring fluorinated components for enhanced performance.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions, nucleophilic substitutions, and as a directing group in metal-catalyzed transformations.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction methodologies and creating compound libraries for screening.

Basic Information

Product Name	Methanesulfonamide, 1,1,1-Trifluoro-n-(3-Fluorophenyl)-
CAS No.	23384-01-2
Molecular Formula	C8H6F4N2O2S
Molecular Weight	270.20 g/mol
Synonyms	N-(3-Fluorophenyl)-1,1,1-trifluoromethanesulfonamide; 1,1,1-Trifluoro-N-(3-fluorophenyl)methanesulfonamide; 3-Fluoro-N-(trifluoromethylsulfonyl)aniline; 1,1,1-Trifluoro-N-(3-fluorophenyl)methane-1-sulfonamide; 3-Fluoroaniline, N-(trifluoromethylsulfonyl)-; Trifluoromethanesulfonanilide, 3'-fluoro-; 3-Fluoro-N-(trifluoromethanesulfonyl)aniline
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, 1,1,1-Trifluoro-n-(3-Fluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.