Description

2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl Cyanide is a key protected ribofuranosyl derivative, widely recognized as a crucial glycosyl donor in nucleoside synthesis. Its primary value lies in enabling the efficient and stereoselective construction of the glycosidic bond, a fundamental step in creating nucleoside analogs. This high-purity intermediate is essential for research and development laboratories in the pharmaceutical and biotechnology sectors, particularly those focused on antiviral, anticancer, and other therapeutic nucleoside-based drugs. The compound, with CAS number 23316-67-8, is supplied to meet the stringent demands of advanced organic synthesis.

Application

• Nucleoside Analog Synthesis: A critical glycosyl donor for the preparation of modified nucleosides used in medicinal chemistry.
• Antiviral Drug Precursor: Serves as a key building block in the synthesis of antiviral agents, including potential candidates for HIV, hepatitis, and herpes treatments.
• Anticancer Agent Development: Used in the research and production of nucleoside-based chemotherapeutic drugs.
• Oligonucleotide Chemistry: Employed in the synthesis of complex oligonucleotides and their analogs for diagnostic and therapeutic applications.
• Pharmaceutical Intermediate: Functions as a high-value intermediate in multi-step synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in academic and industrial R&D for studying enzyme mechanisms and developing novel biochemical probes.

Basic Information

Item	Detail
Product Name	2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl Cyanide
CAS No.	23316-67-8
Molecular Formula	C27H21NO7
Molecular Weight	471.46 g/mol
Synonyms	2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl cyanide; 1-Cyano-2,3,5-tri-O-benzoyl-β-D-ribofuranose; β-D-Ribofuranosyl cyanide, 2,3,5-tribenzoate; Tribenzoyl ribofuranosyl cyanide; 2,3,5-Tri-O-benzoyl-D-ribofuranosyl cyanide; 1-O-Cyano-2,3,5-tri-O-benzoyl-β-D-ribofuranose; 23316-67-8
EINECS	Contact for details

Quality Control

Our 2,3,5-Tri-o-Benzoyl-β-D-Ribofuranosyl Cyanide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.