Description

2-(3-Acetylamino-2,4,6-Triiodophenyl)Butyric Acid is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its molecular structure, featuring a triiodinated aromatic ring, is critical for imparting the high radiopacity required in diagnostic imaging agents. This high-purity intermediate is essential for pharmaceutical manufacturers and advanced research facilities developing next-generation non-ionic, low-osmolar contrast agents to improve patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of iodinated X-ray contrast media, such as iopamidol, iohexol, and other non-ionic derivatives.
• Diagnostic Imaging Agent Precursor: Used in research and production of advanced contrast agents for computed tomography (CT), angiography, and urography.
• Medical Research & Development: Serves as a key starting material in academic and industrial labs for developing novel radiopaque compounds with improved pharmacokinetic profiles.
• Chemical Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and quality control in contrast media manufacturing.

Basic Information

Product Name	2-(3-Acetylamino-2,4,6-Triiodophenyl)Butyric Acid
CAS No.	23279-53-0
Molecular Formula	C12H11I3NO3
Molecular Weight	615.93 g/mol
Synonyms	2-(3-Acetamido-2,4,6-triiodophenyl)butyric acid; 3-Acetylamino-2,4,6-triiodohydrocinnamic acid; 2-(3-Acetamido-2,4,6-triiodophenyl)butanoic acid; NSC 113943; Butyric acid, 2-(3-acetylamino-2,4,6-triiodophenyl)-; α-(3-Acetamido-2,4,6-triiodophenyl)butyric acid; Iopanoic acid intermediate; Contrast media intermediate
EINECS	Contact for details

Quality Control

Our 2-(3-Acetylamino-2,4,6-Triiodophenyl)Butyric Acid is manufactured under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical synthesis. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.