Description

Nifurtimox CAS NO 23256-30-6 is a nitroheterocyclic antiparasitic agent primarily used in the treatment of Chagas disease (American trypanosomiasis). Its significance lies in its potent trypanocidal activity against the *Trypanosoma cruzi* parasite, making it a critical component in global public health initiatives. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers and research institutions developing and producing treatments for neglected tropical diseases.

Application

• Pharmaceutical API: Primary use as the active ingredient in anti-trypanosomal medications for the treatment of Chagas disease.
• Clinical Research: Used in clinical trials and studies focused on new therapeutic regimens, combination therapies, and dosage optimization for trypanosomiasis.
• Veterinary Medicine: Potential application in veterinary parasitology for related trypanosome infections in animals.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Mechanistic Studies: Utilized in biochemical and pharmacological research to study the mechanism of action of nitroheterocyclic compounds against parasites.

Basic Information

Product Name	Nifurtimox
CAS No.	23256-30-6
Molecular Formula	C₁₀H₁₃N₃O₅S
Molecular Weight	287.29 g/mol
Synonyms	Lampit; Bayer 2502; 4-[(5-Nitrofurfurylidene)amino]-3-methylthiomorpholine 1,1-dioxide; 3-Methyl-4-(5'-nitrofurfurylideneamino)tetrahydro-4H-1,4-thiazine 1,1-dioxide; Nitrofurimox; Nifurtimoxum; BAY 2502
EINECS	245-536-8

Quality Control

Our Nifurtimox is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide detailed Certificates of Analysis (COA) that include data for identity, purity, and specified impurities, supporting compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual unspecified impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.