Description

1-[2-[(2,2-Dimethylaziridin-1-Yl)-Difluoro-Methyl]-3,3,3-Trifluoro-2-( Trifluoromethyl)Propyl]Pyrrolidine is a highly fluorinated, specialized organic compound featuring a unique aziridine-pyrrolidine hybrid structure. This compound is valued for its role as a key advanced intermediate in the synthesis of complex molecules, particularly in high-value sectors like pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its specific fluorinated architecture enables precise modifications to enhance metabolic stability, bioavailability, or binding affinity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in developing next-generation herbicides, fungicides, and insecticides where fluorine incorporation improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and coatings, imparting unique surface properties and chemical resistance.
• Ligand & Catalyst Development: The aziridine and pyrrolidine moieties make it a valuable scaffold for creating novel chiral ligands and organocatalysts.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on introducing complex polyfluorinated groups into organic molecules.

Basic Information

Product Name	1-[2-[(2,2-Dimethylaziridin-1-Yl)-Difluoro-Methyl]-3,3,3-Trifluoro-2-( Trifluoromethyl)Propyl]Pyrrolidine
CAS No.	23252-36-0
Molecular Formula	C13H17F8N2
Molecular Weight	353.28 g/mol
Synonyms	2,2-Dimethyl-1-[(3,3,3-trifluoro-2-(trifluoromethyl)-1-(pyrrolidin-1-yl)propan-2-yl)difluoromethyl]aziridine; 1-[2-[(2,2-Dimethyl-1-aziridinyl)difluoromethyl]-3,3,3-trifluoro-2-(trifluoromethyl)propyl]pyrrolidine; Aziridine, 2,2-dimethyl-1-[(3,3,3-trifluoro-2-(trifluoromethyl)-1-(1-pyrrolidinyl)propyl)difluoromethyl]-; Polyfluorinated aziridine-pyrrolidine intermediate
EINECS	Contact for details

Quality Control

Every batch of our 1-[2-[(2,2-Dimethylaziridin-1-Yl)-Difluoro-Methyl]-3,3,3-Trifluoro-2-( Trifluoromethyl)Propyl]Pyrrolidine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties as a strong acid/organic solvent and highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from incompatible materials. For long-term storage, consider using inert gas headspace (e.g., nitrogen or argon) to minimize degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.