Description

Riddelline is a pyrrolizidine alkaloid of significant interest in biochemical and toxicological research. This compound serves as a crucial reference standard and analytical tool for the study of plant toxins and their metabolic pathways. It is primarily utilized by research institutions, pharmaceutical development labs, and regulatory agencies focused on natural product safety and phytochemical analysis.

Application

• Analytical Reference Standard: Used as a primary standard in HPLC, LC-MS, and GC-MS methods for the qualitative and quantitative analysis of pyrrolizidine alkaloids in complex matrices.
• Toxicology Research: Employed in studies investigating the hepatotoxic and genotoxic mechanisms of pyrrolizidine alkaloids, crucial for safety assessments of herbal medicines and food products.
• Phytochemical Profiling: Essential for the identification and characterization of alkaloid content in botanical extracts and plant materials for quality control in the nutraceutical industry.
• Metabolic Studies: Used to investigate the biotransformation and pharmacokinetics of pyrrolizidine alkaloids in in vitro and in vivo models.
• Method Development & Validation: Serves as a critical component in developing and validating new analytical protocols for contaminant detection in compliance with food and drug safety regulations.

Basic Information

Product Name	Riddelline
CAS No.	23246-96-0
Molecular Formula	C18H23NO6
Molecular Weight	349.38 g/mol
Synonyms	Riddelliine; 13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione; (13Z)-Senecionan-11,16-dione, 12,18-dihydroxy-13,19-didehydro-; NSC 236018; Retrorsine N-oxide (related structural class)
EINECS	Contact for details

Quality Control

Our Riddelline is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods. We support compliance with relevant research and analytical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.