Description

3,4-Di-o-Acetyl-2-Fluoro-β-D-Levoglucosan is a high-purity, fluorinated carbohydrate derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in enabling precise stereochemical control in the synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require specialized fluorinated synthons for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the development of novel active pharmaceutical ingredients (APIs), especially nucleoside analogs and glycosidase inhibitors.
• Glycochemistry Research: Used in the study and synthesis of fluorinated sugars and complex carbohydrates to modulate biological activity and metabolic stability.
• Agrochemical Synthesis: Serves as a building block for creating advanced, fluorinated agrochemicals with enhanced efficacy and environmental profiles.
• Diagnostic Probe Development: Employed in the design of molecular probes and imaging agents, leveraging fluorine as a tag for 19F NMR or PET imaging.
• Process Chemistry & Scale-up: Provides a reliable, high-quality intermediate for process optimization and kilogram-to-ton scale manufacturing in regulated environments.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring fluorination chemistry and carbohydrate-based drug design.

Basic Information

Product Name	3,4-Di-o-Acetyl-2-Fluoro-β-D-Levoglucosan
CAS No.	23236-00-2
Molecular Formula	C10H13FO7
Molecular Weight	264.20 g/mol
Synonyms	2-Fluoro-3,4-di-O-acetyl-β-D-arabino-hexos-2-ulo-2,6-pyranose; 2-Fluoro-3,4-di-O-acetyl-β-D-levoglucosan; 1,6-Anhydro-2-fluoro-3,4-di-O-acetyl-β-D-glucopyranose; 3,4-Di-O-acetyl-2-fluoro-β-D-levoglucosan; Fluorinated levoglucosan derivative; 2-Fluoro-levoglucosan diacetate; β-D-Levoglucosan, 3,4-di-O-acetyl-2-fluoro-
EINECS	Contact for details

Quality Control

Our 3,4-Di-o-Acetyl-2-Fluoro-β-D-Levoglucosan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP development and research under ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.