Description

n-Acetylpropargylglycine is a specialized acetylated amino acid derivative featuring a propargyl side chain. This compound serves as a valuable building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceutical agents and biochemical probes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and proteomics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of enzyme inhibitors and targeted therapeutics.
• Bioconjugation & Probe Synthesis: Utilized in click chemistry applications due to its alkyne functionality for labeling biomolecules.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Peptidomimetics: Incorporated into peptide analogs to modulate stability, bioavailability, and biological activity.
• Biochemical Tool Compound: Used in studies investigating amino acid metabolism and related enzymatic pathways.
• Fine Chemical Synthesis: Intermediate for producing more complex, high-value specialty chemicals.

Basic Information

Product Name	n-Acetylpropargylglycine
CAS No.	23234-80-2
Molecular Formula	C₇H₉NO₃
Molecular Weight	155.15 g/mol
Synonyms	N-Acetyl-2-amino-4-pentynoic acid; 2-Acetamido-4-pentynoic acid; Acetylpropargylglycine; N-Acetylpropargylglycine; APG; 2-(Acetylamino)-4-pentynoic acid; N-Acetyl-2-amino-4-pentynoate
EINECS	Contact for details

Quality Control

Our n-Acetylpropargylglycine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.