Description

Boc-Lys(Z)-Gly-Ome is a protected tripeptide derivative widely used as a crucial building block in solid-phase peptide synthesis (SPPS). This compound matters for its role in constructing complex peptide sequences, where the orthogonal protecting groups (Boc and Z) allow for selective deprotection and controlled chain elongation. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled assembly of longer, complex peptide chains in automated synthesizers.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Biochemical Probe Development: Incorporated into peptides used to study enzyme activity, protein-protein interactions, and cellular signaling pathways.
• Custom Peptide Service: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing services.
• Academic Research: Utilized in university laboratories for teaching advanced synthesis techniques and conducting fundamental peptide chemistry studies.

Basic Information

Product Name	Boc-Lys(Z)-Gly-Ome
CAS No.	23234-35-7
Molecular Formula	C₂₃H₃₅N₃O₇
Molecular Weight	465.54 g/mol
Synonyms	Boc-Lys(Z)-Gly-OMe; Nα-Boc-Nε-Cbz-L-lysylglycine methyl ester; tert-Butyloxycarbonyl-Nε-benzyloxycarbonyl-L-lysylglycine methyl ester; Boc-Lys(Cbz)-Gly-OMe; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic Acid; Methyl N-[(2S)-6-[[(2-methylpropan-2-yl)oxycarbonyl]amino]-2-[[(phenylmethoxy)carbonyl]amino]hexanoyl]glycinate; Fmoc-Lys(Boc)-OH (Note: This is a different, common protecting group combination); Benzyl N-[(1S)-5-[[(2-methylpropan-2-yl)oxycarbonyl]amino]-1-[[2-(methoxycarbonyl)ethyl]carbamoyl]pentyl]carbamate
EINECS	Contact for details

Quality Control

Our Boc-Lys(Z)-Gly-Ome is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR/IR for structural confirmation, to ensure compliance with research and pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.