Description

4-[3-(2-Chloro-10H-Phenothiazin-10-Yl)Propyl]Piperazine-1-Ethanol Hydrochloride is a high-purity, pharmacologically significant phenothiazine derivative. This compound is a critical advanced intermediate in the synthesis of active pharmaceutical ingredients (APIs), valued for its precise chemical structure and purity. It is essential for research and manufacturing within the pharmaceutical industry, particularly for developing neuropsychiatric and antihistaminic therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of phenothiazine-class antipsychotic and antihistamine drugs.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor in medicinal chemistry for developing new central nervous system (CNS) agents.
• Biochemical Research: Used in pharmacological studies to investigate receptor binding and mechanism of action.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method development.
• Process Development: Utilized in scaling up and optimizing synthetic routes for pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	4-[3-(2-Chloro-10H-Phenothiazin-10-Yl)Propyl]Piperazine-1-Ethanol Hydrochloride
CAS No.	23221-95-6
Molecular Formula	C21H27ClN3OS • HCl
Molecular Weight	434.88 g/mol
Synonyms	Perphenazine Impurity; 1-[2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethanol dihydrochloride; 10-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl]-2-chlorophenothiazine dihydrochloride; 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine dihydrochloride; Perphenazine Related Compound; 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-[3-(2-Chloro-10H-Phenothiazin-10-Yl)Propyl]Piperazine-1-Ethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) that detail all specifications and test results, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.