Description

2-[3-(n-Ethylacetylamino)-2,4,6-Triiodophenyl]Valeric Acid is a high-purity iodinated organic compound, serving as a critical intermediate in the synthesis of advanced X-ray contrast media. Its value lies in enabling the production of safe and effective diagnostic agents with high radiopacity. This product is essential for pharmaceutical manufacturers and research institutions developing next-generation non-ionic contrast agents for medical imaging procedures such as angiography, urography, and computed tomography (CT) scans.

Application

• Primary Intermediate for synthesizing non-ionic X-ray contrast agents like Iopamidol and Ioversol.
• Pharmaceutical Research & Development for novel iodinated contrast media with improved safety profiles.
• Active Pharmaceutical Ingredient (API) Manufacturing in cGMP facilities.
• Chemical Reference Standard for quality control and analytical method development.
• Precursor for Radiolabeling Studies in diagnostic imaging research.

Basic Information

Product Name	2-[3-(n-Ethylacetylamino)-2,4,6-Triiodophenyl]Valeric Acid
CAS No.	23217-88-1
Molecular Formula	C15H19I3N2O3
Molecular Weight	647.04 g/mol
Synonyms	5-[3-(Acetylethylamino)-2,4,6-triiodobenzoyl]pentanoic Acid; N-Ethyl-2,4,6-triiodo-5-(4-carboxybutanoyl)-3-pyridinecarboxamide (obsolete); Iopamidol Intermediate; Ioversol Intermediate; 23217-88-1; Valeric acid, 2-[3-(N-ethylacetamido)-2,4,6-triiodophenyl]-; 5-[3-(Acetylethylamino)-2,4,6-triiodobenzoyl]valeric Acid
EINECS	Contact for details

Quality Control

Our 2-[3-(n-Ethylacetylamino)-2,4,6-Triiodophenyl]Valeric Acid is manufactured under strict quality management systems. We provide material that meets exacting standards for pharmaceutical intermediate applications, with typical purity levels exceeding 98.5% (HPLC). A comprehensive Certificate of Analysis (COA) is supplied with each batch, detailing identity, purity, and impurity profiles. Our quality commitment aligns with ICH guidelines and supports cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.