Description

2-(3-Acetylamino-2,4,6-Triiodophenyl)Propionic Acid is a high-purity iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its molecular structure, featuring three iodine atoms, is critical for imparting the radiopacity required in diagnostic imaging agents. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors developing non-ionic, low-osmolar contrast agents for enhanced patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: Primary building block for synthesizing advanced X-ray and CT scan contrast media, such as Iopromide and Ioversol derivatives.
• Diagnostic Imaging Agent Precursor: Serves as the core iodinated aromatic moiety in the production of non-ionic, low-osmolar contrast agents.
• Research & Development: Used in academic and industrial R&D for developing new radiopaque compounds and studying structure-activity relationships.
• Fine Chemical Synthesis: Intermediate in multi-step organic syntheses requiring specific, high-value iodinated aromatic structures.
• Contrast Media Formulation: Critical for ensuring the final pharmaceutical product meets strict standards for opacity, solubility, and biocompatibility.

Basic Information

Product Name	2-(3-Acetylamino-2,4,6-Triiodophenyl)Propionic Acid
CAS No.	23217-81-4
Molecular Formula	C11H9I3NO3
Molecular Weight	601.91 g/mol
Synonyms	3-Acetamido-2,4,6-triiodohydrocinnamic Acid; 2-[3-(Acetylamino)-2,4,6-triiodophenyl]propanoic Acid; α-Methyl-3-acetamido-2,4,6-triiodohydrocinnamic Acid; Iopromide Intermediate; Ioversol Intermediate; Non-Ionic Contrast Media Intermediate; 23217-81-4; NSC 401564
EINECS	Contact for details

Quality Control

Our 2-(3-Acetylamino-2,4,6-Triiodophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical intermediate applications. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.