Description

2-[3-(n-Methylacetylamino)-2,4,6-Triiodophenoxy]-2-(o-Tolyl)Acetic Acid is a specialized iodinated organic compound with a complex molecular structure designed for high-performance applications. This chemical is critical for businesses requiring advanced intermediates in the synthesis of X-ray contrast media and other diagnostic imaging agents. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) focused on developing next-generation medical imaging solutions.

Application

• Key Intermediate for X-ray Contrast Agents: Serves as a crucial building block in the synthesis of non-ionic, low-osmolar contrast media used in computed tomography (CT) and angiography.
• Pharmaceutical Research & Development: Used in the discovery and development of novel iodinated compounds for enhanced imaging diagnostics.
• Fine Chemical Synthesis: Acts as a high-value intermediate in multi-step organic synthesis for specialized chemical libraries.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of active pharmaceutical ingredients (APIs) in diagnostic applications.
• Radiology Agent Precursor: A precursor molecule for agents designed to provide clear visualization of vascular structures and organs.

Basic Information

Product Name	2-[3-(n-Methylacetylamino)-2,4,6-Triiodophenoxy]-2-(o-Tolyl)Acetic Acid
CAS No.	23197-57-1
Molecular Formula	C18H17I3NO4
Molecular Weight	677.05 g/mol
Synonyms	2-[3-(N-Methylacetamido)-2,4,6-triiodophenoxy]-2-(2-methylphenyl)acetic acid; 2-(o-Tolyl)-2-[3-(N-methylacetamido)-2,4,6-triiodophenoxy]acetic acid; Acetic acid, 2-[3-(N-methylacetamido)-2,4,6-triiodophenoxy]-2-(2-methylphenyl)-; Iopamidol Intermediate; Iopamidol Related Compound; Non-ionic Contrast Media Intermediate; Iodinated Phenoxyacetic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of 2-[3-(n-Methylacetylamino)-2,4,6-Triiodophenoxy]-2-(o-Tolyl)Acetic Acid adheres to stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, and we support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredient (API) manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.