Description

2-[3-(Acetylamino)-2,4,6-Triiodophenoxy]-2-(p-Iodophenyl)Acetic Acid is a high-purity, iodinated organic compound primarily utilized as a key intermediate in the synthesis of advanced contrast media. This compound is critical for ensuring the quality and efficacy of final pharmaceutical formulations used in diagnostic imaging. It is essential for manufacturers and R&D facilities in the pharmaceutical and fine chemical sectors requiring precise and reliable building blocks for X-ray and CT contrast agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of non-ionic, iodinated X-ray contrast media such as iopamidol, iohexol, and related compounds.
• Diagnostic Imaging Agent Synthesis: Serves as a core precursor for developing advanced contrast agents used in computed tomography (CT), angiography, and urography.
• Fine Chemical Research: Used in organic synthesis and medicinal chemistry research for creating novel iodinated molecules with potential diagnostic or therapeutic applications.
• Contrast Media Production: Integral to the manufacturing process of final drug products, ensuring high radiocontrast and patient safety profiles.
• Quality Control & Reference Standard: Can be employed as a reference standard in analytical laboratories for method development and impurity profiling of contrast agents.

Basic Information

Product Name	2-[3-(Acetylamino)-2,4,6-Triiodophenoxy]-2-(p-Iodophenyl)Acetic Acid
CAS No.	23189-41-5
Molecular Formula	C16H12I4NO4
Molecular Weight	835.89 g/mol
Synonyms	2-[3-(Acetylamino)-2,4,6-triiodophenoxy]-2-(4-iodophenyl)acetic acid; Acetic acid, 2-[3-(acetylamino)-2,4,6-triiodophenoxy]-2-(4-iodophenyl)-; 2-(4-Iodophenyl)-2-[3-(acetylamino)-2,4,6-triiodophenoxy]acetic acid; Iopamidol Intermediate; Iohexol Intermediate; AD-01; Iodinated Contrast Media Intermediate; 4-Acetamido-2,6-diiodo-3-(4-iodophenylacetoxy)phenol derivative
EINECS	Contact for details

Quality Control

Our 2-[3-(Acetylamino)-2,4,6-Triiodophenoxy]-2-(p-Iodophenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.