Description

1,1-Difluorocyclooctane is a fluorinated cyclic alkane characterized by its unique structural motif, which imparts specific chemical and physical properties valuable in advanced synthesis. This compound serves as a versatile fluorinated building block and intermediate, enabling the introduction of fluorine atoms into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications requiring fluorinated scaffolds.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly where fluorination is employed to modulate metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Acts as a key precursor in developing new fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Fluorinated Material Synthesis: Serves as a monomer or modifier in the production of specialty polymers, coatings, and liquid crystals with enhanced chemical resistance, thermal stability, or optical properties.
• Organic Synthesis Building Block: Employed in medicinal and synthetic chemistry for ring-opening reactions, cross-coupling, and as a source of difluoromethylene units to create complex fluoroorganic molecules.
• Catalysis & Ligand Development: Investigated for use in developing novel fluorinated ligands for metal catalysis, which can influence reaction selectivity and efficiency.
• Electrolyte Additive Research: Explored in advanced battery systems, such as lithium-ion batteries, where fluorinated compounds can improve electrolyte stability and performance.

Basic Information

Product Name	1,1-Difluorocyclooctane
CAS No.	23170-87-8
Molecular Formula	C8H14F2
Molecular Weight	148.19 g/mol
Synonyms	Cyclooctane, 1,1-difluoro-; 1,1-Difluorocyclooctane; Difluorocyclooctane; Octamethylene Fluoride; Perfluorocyclooctane (incorrect but common alias); Fluorocarbon C-8; F-Cyclooctane
EINECS	Contact for details

Quality Control

Our 1,1-Difluorocyclooctane is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from direct heat and ignition sources. Due to its highly volatile nature and classification as a fluoride/strong alkali reactive compound, keep the container tightly sealed when not in use and separate from incompatible materials such as strong acids and oxidizers. Recommended storage temperature is 2-8°C (refrigerated) or as specified on the label to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.0 g/mL
Boiling Point	Contact for details
Refractive Index (n20D)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.