Description

.Beta.-D-Glucopyranose, 1,6-Anhydro-2-Deoxy-2-Fluoro-4-o-(Phenylmethyl)- is a high-purity fluorinated carbohydrate derivative, a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its role as a crucial building block for the synthesis of novel nucleoside analogs and fluorinated sugar-based therapeutics, enabling the exploration of new drug candidates with enhanced metabolic stability and bioavailability. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries focused on antiviral, anticancer, and diagnostic agent discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs for antiviral and anticancer drug development.
• Probe & Diagnostic Development: Used in the creation of molecular probes and imaging agents, particularly Positron Emission Tomography (PET) tracers, leveraging the fluorine-18 isotope.
• Glycobiology Research: Serves as a specialized substrate or inhibitor for studying glycosidase enzymes and carbohydrate-processing pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to modify the pharmacokinetic properties of sugar-containing drug molecules.
• Process Chemistry & Scale-up: Used in the development and optimization of scalable synthetic routes for complex fluorinated active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Acts as a chiral building block for the asymmetric synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	.Beta.-D-Glucopyranose, 1,6-Anhydro-2-Deoxy-2-Fluoro-4-o-(Phenylmethyl)-
CAS No.	23094-75-9
Molecular Formula	C₁₃H₁₅FO₄
Molecular Weight	254.26 g/mol
Synonyms	1,6-Anhydro-2-deoxy-2-fluoro-4-O-benzyl-β-D-glucopyranose; 2-Deoxy-2-fluoro-4-O-benzyl-1,6-anhydro-β-D-glucopyranose; 4-O-Benzyl-2-deoxy-2-fluoro-1,6-anhydro-β-D-glucopyranose; 2-Fluoro-4-O-benzyl-1,6-anhydro-β-D-glucopyranose; Benzyl 2-deoxy-2-fluoro-β-D-glucopyranoside 4,6-cyclic sulfate (related precursor); Fluorinated levoglucosan derivative; 4-O-Benzyl-2-fluoro-levoglucosan
EINECS	Contact for details

Quality Control

Our production of .Beta.-D-Glucopyranose, 1,6-Anhydro-2-Deoxy-2-Fluoro-4-o-(Phenylmethyl)- adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key specifications such as assay (HPLC), chiral purity, and impurity profiles are provided with every shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure storage areas are separate from such materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.