Description

4-Chloro-3-(Trifluoromethyl)Phenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a chloro and a trifluoromethyl substituent, makes it a critical intermediate for creating compounds with enhanced biological activity and physicochemical properties. This high-purity intermediate is primarily sought by the pharmaceutical and agrochemical industries for research and development, as well as for the production of active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes due to its ability to modify electronic properties.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where halogen and fluorine substitutions alter color fastness and spectral characteristics.

Basic Information

Item	Detail
Product Name	4-Chloro-3-(Trifluoromethyl)Phenylacetic Acid
CAS No.	22902-86-9
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	2-(4-Chloro-3-(trifluoromethyl)phenyl)acetic Acid; 4-Chloro-α,α,α-trifluoro-m-toluic Acid (related isomer); 2-(4-Chloro-3-trifluoromethylphenyl)acetic Acid; 4-Chloro-3-trifluoromethylbenzeneacetic Acid; p-Chloro-m-(trifluoromethyl)phenylacetic Acid; (4-Chloro-3-(trifluoromethyl)phenyl)acetic Acid; 22902-86-9 (CAS); CTFPA
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Phenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, appropriate chemical-resistant materials should be used for handling and storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.