Description

2-Chloro-3-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced chemical entities with tailored properties. This compound is primarily sought after by research and development teams and process chemists in the agrochemical and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, particularly in creating molecules with improved metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for producing fluorinated components used in electronic displays and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and durability.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and cyano-group transformations to construct complex heterocyclic and aromatic systems.

Basic Information

Product Name	2-Chloro-3-(Trifluoromethyl)Phenylacetonitrile
CAS No.	22902-81-4
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	2-Chloro-α-(trifluoromethyl)benzeneacetonitrile; (2-Chloro-3-(trifluoromethyl)phenyl)acetonitrile; 2-Chloro-3-trifluoromethylbenzyl cyanide; α-Chloro-α-(trifluoromethyl)phenylacetonitrile (related isomer); 2-Chloro-3-(trifluoromethyl)benzenecetonitrile; 22902-81-4; 2-Chloro-α-(trifluoromethyl)phenylacetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-(Trifluoromethyl)Phenylacetonitrile is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.