Description

Acetamide, n-(2-Aminophenyl)-2,2,2-Trifluoro- is a specialized trifluoroacetamide derivative featuring an ortho-aminophenyl substituent, a structure that imparts unique reactivity and functional properties. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for the construction of complex heterocyclic systems and functional materials. It is primarily required by pharmaceutical R&D, agrochemical innovators, and specialty chemical manufacturers seeking to develop novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Functional Material Development: Used in the research and production of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing trifluoroacetyl group and aromatic amine functionality.
• Dye and Pigment Chemistry: Intermediate for synthesizing complex azo dyes and high-performance pigments requiring specific light-fastness and color properties.
• Chemical Research & Development: Serves as a model compound and starting material in academic and industrial research for studying reaction mechanisms and developing new synthetic methodologies.
• Ligand and Catalyst Preparation: Useful for constructing chelating ligands in coordination chemistry and catalysis, leveraging the amine and amide donor sites.

Basic Information

Product Name	Acetamide, n-(2-Aminophenyl)-2,2,2-Trifluoro-
CAS No.	22902-31-4
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	N-(2-Aminophenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-aminophenyl)acetamide; 2-Amino-2',2',2'-trifluoroacetanilide; 2'-Amino-α,α,α-trifluoroacetanilide; o-Aminophenyltrifluoroacetamide; 1-Amino-2-(trifluoroacetamido)benzene; 2-(Trifluoroacetamido)aniline; TFAA-o-Phenylenediamine adduct
EINECS	Contact for details

Quality Control

Our Acetamide, n-(2-Aminophenyl)-2,2,2-Trifluoro- is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. Certificates of Analysis (COA) detailing all critical quality attributes are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.