Description

2-Chloro-5-(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, combining a phenylacetic acid core with chloro and trifluoromethyl substituents, makes it a critical intermediate for creating molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Employed to introduce functional aromatic and fluorinated groups into polymer chains, altering thermal and chemical resistance properties.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions and other catalytic processes for constructing complex molecular architectures in R&D settings.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	22893-39-6
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	2-Chloro-α-(trifluoromethyl)benzeneacetic Acid; [2-Chloro-5-(trifluoromethyl)phenyl]acetic Acid; α-(2-Chloro-5-(trifluoromethyl)phenyl)acetic Acid; 2-Chloro-5-(trifluoromethyl)benzeneacetic Acid; 2-Chloro-5-trifluoromethylphenylacetic Acid; (2-Chloro-5-(trifluoromethyl)phenyl)acetic acid; 2-Chloro-α,α,α-trifluoro-m-toluic Acid (related); CTFPA
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	105°C - 110°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.