Description

Quetiapine Dbto Sulfone is a key pharmaceutical intermediate and reference standard of significant importance in the development and quality control of active pharmaceutical ingredients (APIs). This compound is critical for ensuring the purity, efficacy, and safety of related drug substances and final formulations. It is primarily utilized by research institutions, analytical laboratories, and manufacturers within the global pharmaceutical and life sciences industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and related compounds.
• Analytical Reference Standard: Used for method development, validation, and quality control testing in HPLC, GC, and other chromatographic analyses.
• Impurity Standard: Serves as a certified reference material for the identification and quantification of process-related impurities and degradation products.
• Research & Development: Employed in preclinical and clinical research for metabolic studies, pharmacokinetic profiling, and stability testing.
• Regulatory Compliance: Supports regulatory filings by providing well-characterized materials for stability studies and specification setting.
• Custom Synthesis: Acts as a starting material or precursor for the custom synthesis of novel chemical entities and derivatives.

Basic Information

Product Name	Quetiapine Dbto Sulfone
CAS No.	22871-33-6
Molecular Formula	C21H25N3O2S2
Molecular Weight	415.57 g/mol
Synonyms	Quetiapine Sulfone; Quetiapine Dibenzoothiepine Sulfone; 11-(4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl)dibenzo[b,f][1,4]thiazepine 5,5-Dioxide; DBTO Sulfone of Quetiapine; Quetiapine Related Compound; Quetiapine Impurity; ICI 204,636 Sulfone
EINECS	Contact for details

Quality Control

Our Quetiapine Dbto Sulfone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC to ensure it meets high-purity standards suitable for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.