Description

4-(Methylsulfonyl)Benzonitrile is a high-value, multi-functional aromatic nitrile derivative characterized by its methylsulfonyl substituent. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block, enabling the construction of complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science: Monomer or additive for high-performance polymers and liquid crystal materials.
• Organic Electronics: Intermediate in the synthesis of electron-accepting units for organic semiconductors.
• Chemical Research: Versatile substrate for exploring novel sulfone and nitrile chemistry in academic and industrial R&D.

Basic Information

Product Name	4-(Methylsulfonyl)Benzonitrile
CAS No.	22821-76-7
Molecular Formula	C8H7NO2S
Molecular Weight	181.21 g/mol
Synonyms	4-(Methylsulfonyl)benzonitrile; p-(Methylsulfonyl)benzonitrile; 4-Methanesulfonylbenzonitrile; 4-Cyanophenyl methyl sulfone; Methyl 4-cyanophenyl sulfone; Benzonitrile, 4-(methylsulfonyl)-; 22821-76-7; p-Cyanophenyl methyl sulfone
EINECS	Contact for details

Quality Control

Our production of 4-(Methylsulfonyl)Benzonitrile adheres to stringent cGMP and ISO 9001 quality management principles. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.