Description

2-[2-(3-Acetamido-2,4,6-Triiodo-Phenoxy)Ethoxy]Propanoic Acid is a high-purity iodinated organic compound, a key intermediate in the synthesis of modern X-ray contrast media. Its precise molecular structure is critical for ensuring the safety and efficacy of the final diagnostic agents. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries developing non-ionic, low-osmolar contrast media for enhanced patient safety during medical imaging procedures.

Application

• Primary Intermediate in the synthesis of non-ionic X-ray contrast agents such as Iopamidol, Ioversol, and Iopromide.
• Pharmaceutical Research & Development for creating novel iodinated contrast media with improved safety profiles.
• Fine Chemical Synthesis for building complex molecules requiring a triiodinated aromatic core.
• Contrast Media Manufacturing, serving as a critical building block in GMP production processes.
• Diagnostic Imaging Agent Development for CT scans, angiography, and other radiographic procedures.

Basic Information

Item	Detail
Product Name	2-[2-(3-Acetamido-2,4,6-Triiodo-Phenoxy)Ethoxy]Propanoic Acid
CAS No.	22730-89-8
Molecular Formula	C13H14I3NO5
Molecular Weight	688.97 g/mol
Synonyms	3-Acetamido-2,4,6-triiodo-5-[2-(2-methoxyethoxy)ethoxy]benzoic Acid; 5-[2-(2-Methoxyethoxy)ethoxy]-3-acetamido-2,4,6-triiodobenzoic Acid; Iopamidol Intermediate; Ioversol Intermediate; Iopromide Intermediate; 22730-89-8; ATIPA
EINECS	Contact for details

Quality Control

Our 2-[2-(3-Acetamido-2,4,6-Triiodo-Phenoxy)Ethoxy]Propanoic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and heavy metal analysis, to ensure it meets the high-purity standards required for pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.