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2-[3-[[2-(3-Amino-2,4,6-Triiodo-Phenyl)Acetyl]Amino]Phenoxy]Propanoic Acid CAS NO 22708-54-9


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CAS No.:22708-54-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[3-[[2-(3-Amino-2,4,6-Triiodo-Phenyl)Acetyl]Amino]Phenoxy]Propanoic Acid is a high-purity, iodinated organic compound primarily used as a key intermediate in advanced pharmaceutical synthesis. Its molecular structure, featuring a triiodinated aromatic ring, makes it a critical building block for developing specialized contrast agents and diagnostic imaging pharmaceuticals. This compound is essential for manufacturers and R&D facilities in the pharmaceutical and fine chemical sectors requiring precise, high-quality intermediates for complex synthesis pathways.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of iodinated X-ray and CT (Computed Tomography) contrast media agents.
  • Diagnostic Imaging Agent Synthesis: Used in the research and development of novel non-ionic, low-osmolar contrast agents for enhanced patient safety and image clarity.
  • Fine Chemical Research: Serves as a specialized building block in organic synthesis for creating complex molecules with specific iodine-containing functional groups.
  • Bioconjugation Studies: Potential use in developing labeled compounds for research in molecular imaging and targeted drug delivery systems.
  • Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Item Detail
Product Name 2-[3-[[2-(3-Amino-2,4,6-Triiodo-Phenyl)Acetyl]Amino]Phenoxy]Propanoic Acid
CAS No. 22708-54-9
Molecular Formula C17H15I3N2O4
Molecular Weight 683.02 g/mol
Synonyms 3-Acetamido-2,4,6-triiodo-5-[(2-methoxyethoxy)acetyl]aminobenzoic Acid (common process intermediate name); 5-[3-[[2-(3-Amino-2,4,6-triiodophenyl)acetyl]amino]phenoxy]propanoic Acid; Iodinated Benzoic Acid Derivative; Contrast Agent Intermediate; Iohexol/ Iopamidol Related Intermediate; ATIPA; CAS 22708-54-9
EINECS Contact for details

Quality Control

Our 2-[3-[[2-(3-Amino-2,4,6-Triiodo-Phenyl)Acetyl]Amino]Phenoxy]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC) Meets ICH Q3C guidelines
Heavy Metals ≤ 20 ppm
Loss on Drying ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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