Description

2-[4-[[3-(Acetyl-Ethyl-Amino)-2,4,6-Triiodo-Benzoyl]Amino]Phenyl]Acetic Acid is a high-purity, triiodinated organic compound primarily used as a key intermediate in the synthesis of advanced X-ray contrast media. Its complex molecular structure, featuring a benzoyl acetic acid core, is engineered to provide excellent water solubility and targeted biodistribution in final pharmaceutical formulations. This product is essential for manufacturers in the diagnostic imaging sector who require reliable, high-quality building blocks for producing non-ionic, low-osmolar contrast agents.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of iodinated X-ray contrast agents for computed tomography (CT) and angiography.
• Diagnostic Imaging Agent Synthesis: Building block for non-ionic, monomeric contrast media known for improved patient tolerance and safety profiles.
• Research & Development: Used in academic and industrial R&D for developing novel radiopaque compounds and studying structure-activity relationships.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Specialty Chemical Synthesis: Intermediate for creating other iodinated aromatic compounds with potential applications in material science or other diagnostic fields.

Basic Information

Product Name	2-[4-[[3-(Acetyl-Ethyl-Amino)-2,4,6-Triiodo-Benzoyl]Amino]Phenyl]Acetic Acid
CAS No.	22708-43-6
Molecular Formula	C19H16I3N2O4
Molecular Weight	739.06 g/mol
Synonyms	AE-131; Ioxitalamic Acid Impurity; 2-[4-[[3-(Acetylethylamino)-2,4,6-triiodobenzoyl]amino]phenyl]acetic acid; N-Acetyl-N-ethyl-3-amino-2,4,6-triiodo-5-[(carboxymethyl)carbamoyl]benzoic Acid; Benzoic acid, 3-(acetylethylamino)-2,4,6-triiodo-5-[(carboxymethyl)carbamoyl]-; AE131; Intermediate of Ioxitalamic Acid
EINECS	Contact for details

Quality Control

Our 2-[4-[[3-(Acetyl-Ethyl-Amino)-2,4,6-Triiodo-Benzoyl]Amino]Phenyl]Acetic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to support regulatory filings (e.g., DMF, CEP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.