Description

n-[4-(Methylthio)Phenyl]-3,4,5-Trimethoxybenzamide is a high-purity synthetic organic compound belonging to the benzamide class, featuring a trimethoxybenzoyl core linked to a methylthiophenyl group. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a key scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and process development stages for new APIs, especially those with modified benzamide structures.
• Biochemical Research: May be utilized as a tool compound or inhibitor in biochemical assays to study specific enzyme or receptor interactions.
• Fine Chemical Synthesis: Acts as a specialized intermediate for synthesizing more complex, high-value fine chemicals and functional materials.

Basic Information

Product Name	n-[4-(Methylthio)Phenyl]-3,4,5-Trimethoxybenzamide
CAS No.	22708-26-5
Molecular Formula	C17H19NO4S
Molecular Weight	333.40 g/mol
Synonyms	4-Methylthio-N-(3,4,5-trimethoxybenzoyl)aniline; 3,4,5-Trimethoxy-N-[4-(methylthio)phenyl]benzamide; N-(4-Methylthiophenyl)-3,4,5-trimethoxybenzamide; Benzamide, N-[4-(methylthio)phenyl]-3,4,5-trimethoxy-; 22708-26-5; 4-(Methylmercapto)benzanilide, 3,4,5-trimethoxy-
EINECS	Contact for details

Quality Control

Our n-[4-(Methylthio)Phenyl]-3,4,5-Trimethoxybenzamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.