Description

(H-Cys-NH2)2 2 HCl is a high-purity, protected derivative of the amino acid L-cysteine, specifically the dihydrochloride salt of L-cystine diamide. This compound is a critical building block in peptide synthesis and pharmaceutical research, offering a protected thiol group for controlled chemical manipulation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for developing novel therapeutics and bioactive molecules.

Application

• Peptide Synthesis Intermediate: A key protected precursor for the controlled incorporation of cysteine residues into synthetic peptides and proteins.
• Pharmaceutical Research: Used in the development and scale-up of active pharmaceutical ingredients (APIs) that contain disulfide bridges or require specific thiol chemistry.
• Bioconjugation Chemistry: Serves as a starting material for creating linkers and cross-linking agents used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Biochemical Research: Employed in studies of protein folding, disulfide bond formation, and redox biology.
• Fine Chemical Synthesis: A versatile chiral building block for synthesizing complex organic molecules and catalysts.

Basic Information

Product Name	(H-Cys-NH2)2 2 HCl
CAS No.	22671-21-2
Molecular Formula	C6H16Cl2N4O2S2
Molecular Weight	319.26 g/mol
Synonyms	L-Cystine diamide dihydrochloride; Cystine Diamide Dihydrochloride; H-Cys-NH2.HCl dimer; Bis(L-cysteine amide) dihydrochloride; (S,S)-2,2'-Diamino-3,3'-dithiodipropionamide dihydrochloride; NSC 3349; (H-Cys-NH2)2•2HCl
EINECS	Contact for details

Quality Control

Our (H-Cys-NH2)2 2 HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.