Description

Ibutilidefumarate is a high-purity pharmaceutical active ingredient, a salt form of the class III antiarrhythmic agent Ibutilide. This compound is critical for the formulation of injectable medications used to treat specific cardiac arrhythmias. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of life-saving cardiovascular drugs.

Application

• Pharmaceutical API: As the active pharmaceutical ingredient (API) in injectable formulations for the rapid conversion of atrial fibrillation and atrial flutter of recent onset.
• Cardiovascular Research: A key reference standard and tool compound in preclinical and clinical research studying cardiac electrophysiology and antiarrhythmic drug mechanisms.
• Analytical Standard: Used as a certified reference material (CRM) in quality control laboratories for method development, validation, and assay calibration.
• Formulation Development: Employed in the R&D of new drug delivery systems, dosage forms, and combination therapies targeting heart rhythm disorders.

Basic Information

Product Name	Ibutilidefumarate
CAS No.	22647-32-9
Molecular Formula	C24H38N2O6S
Molecular Weight	482.63 g/mol
Synonyms	Ibutilide Fumarate; Ibutilide Hydrogen Fumarate; (N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamide) Fumarate; U-70226E; Corvert (brand name associated with the drug product); 4-[4-(Ethyloctylamino)-1-hydroxybutyl]phenyl]methanesulfonamide fumarate; EINECS Contact for details

Quality Control

Our Ibutilidefumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, suitable for pharmaceutical applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and compliance with cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.