Description

N(2)-Acetyl-N(6)-(2,4-Dinitrophenyl)Lysine is a specialized, high-purity chemical derivative of lysine, modified with acetyl and 2,4-dinitrophenyl (DNP) protecting groups. This compound is critical for advanced biochemical research and pharmaceutical development, particularly in the study of protein structure, function, and post-translational modifications. It serves as a key intermediate and analytical standard for researchers and manufacturers in proteomics, enzymology, and the production of novel therapeutic agents.

Application

• Biochemical Research: Used as a protected amino acid derivative in peptide synthesis and as a standard in protein chemistry studies.
• Proteomics & Enzymology: Acts as a substrate or inhibitor analog in enzymatic assays to study lysine-specific modifications like acetylation and deacetylation.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of more complex molecules for drug discovery programs.
• Analytical Standards: Provides a high-purity reference material for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Antibody & Diagnostic Development: Can be used to conjugate to carrier proteins for generating antibodies specific to DNP-modified lysine residues.
• Academic & Industrial R&D: Essential for fundamental research in biochemistry and molecular biology within universities, CROs, and biotech companies.

Basic Information

Item	Details
Product Name	N(2)-Acetyl-N(6)-(2,4-Dinitrophenyl)Lysine
CAS No.	22619-87-0
Molecular Formula	C15H19N4O7
Molecular Weight	367.34 g/mol
Synonyms	Nε-(2,4-Dinitrophenyl)-Nα-acetyl-L-lysine; Ac-Lys(DNP)-OH; Nα-Acetyl-Nε-(2,4-dinitrophenyl)-L-lysine; N-Acetyl-N-(2,4-dinitrophenyl)lysine; L-Lysine, N2-acetyl-N6-(2,4-dinitrophenyl)-; N-Acetyl-DNP-lysine; DNP-Ac-Lys; Acetyl-DNP-lysine
EINECS	Contact for details

Quality Control

Our N(2)-Acetyl-N(6)-(2,4-Dinitrophenyl)Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.