Description

(22R)-2β,3β,20,22,25-Pentahydroxy-5β-Cholesta-8,14-Dien-6-One is a high-purity, multi-hydroxylated steroidal compound of significant interest in advanced pharmaceutical research and synthesis. This specialized intermediate is valued for its complex molecular architecture, which serves as a critical scaffold for the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in steroid chemistry, metabolic pathway studies, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in metabolic studies, enzyme inhibition assays, and investigations into cholesterol biosynthesis pathways.
• Organic Synthesis: Serves as a complex starting material or building block for the total synthesis of natural products and other steroidal derivatives.
• Academic & R&D Laboratories: Employed in universities and corporate R&D centers for fundamental chemical research and method development.

Basic Information

Product Name	(22R)-2β,3β,20,22,25-Pentahydroxy-5β-Cholesta-8,14-Dien-6-One
CAS No.	22612-27-7
Molecular Formula	C₂₇H₄₂O₆
Molecular Weight	462.62 g/mol
Synonyms	22R-Hydroxyecdysone; 2β,3β,20R,22R,25-Pentahydroxy-5β-cholest-8(14)-en-6-one; Integristerone A; 22R-Isomer of Ecdysterone; (22R)-Ecdysone; 5β-Cholesta-8,14-diene-2β,3β,20,22,25-pentol-6-one, (22R)-; 22612-27-7; EINECS 245-124-8
EINECS	245-124-8

Quality Control

Our (22R)-2β,3β,20,22,25-Pentahydroxy-5β-Cholesta-8,14-Dien-6-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.