Description

Indan, 5,5-Difluorohexahydro-, cis- (8Ci) is a specialized fluorinated indan derivative, a high-value building block in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine atoms, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, where the cis-configuration and fluorination pattern are critical for specific activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the synthesis of advanced electronic materials for displays and lighting.
• Catalyst & Ligand Development: Employed in the design of new chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reference compound and starting material for academic and industrial research into new fluorination methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	Indan, 5,5-Difluorohexahydro-, cis- (8Ci)
CAS No.	22578-06-9
Molecular Formula	C9H14F2
Molecular Weight	160.21 g/mol
Synonyms	cis-5,5-Difluorohexahydroindan; Hexahydro-5,5-difluoroindan, cis-; 5,5-Difluorohexahydro-1H-indene; (3aS,7aR)-5,5-Difluorohexahydro-1H-indene; 1H-Indene, 5,5-difluorohexahydro-, cis-; 22578-06-9; cis-5,5-Difluoroperhydroindane
EINECS	Contact for details

Quality Control

Every batch of Indan, 5,5-Difluorohexahydro-, cis- (8Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (GC, HPLC, NMR) are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong alkalis and fluorides. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Isomer Ratio (cis/trans)	≥ 95:5 (by GC or NMR)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.