Description

n-(p-Nitrobenzoyl)Glutamic Acid CAS NO 22536-03-4 is a high-purity, specialty organic compound that serves as a critical chiral building block and intermediate in advanced chemical synthesis. Its unique molecular structure, featuring both a nitrobenzoyl group and a glutamic acid moiety, makes it invaluable for the development of complex molecules with specific stereochemistry. This product is essential for research and production in the pharmaceutical and fine chemical industries, where precise molecular architecture is required for active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for targeted drug molecules.
• Peptide Synthesis: Used in the preparation of modified peptides and peptidomimetics, where the nitrobenzoyl group can serve as a protective moiety or a functional handle.
• Bioconjugation Chemistry: Acts as a linker or spacer molecule for attaching functional groups to biomolecules in diagnostic and research applications.
• Chemical Research: Employed in academic and industrial laboratories for studying reaction mechanisms and developing new synthetic methodologies.
• Fine Chemical Production: Serves as a precursor for the manufacture of other high-value, nitro-aromatic or glutamic acid-derived specialty chemicals.

Basic Information

Product Name	n-(p-Nitrobenzoyl)Glutamic Acid
CAS No.	22536-03-4
Molecular Formula	C12H12N2O7
Molecular Weight	296.24 g/mol
Synonyms	N-(4-Nitrobenzoyl)-L-glutamic Acid; (2S)-2-[(4-Nitrobenzoyl)amino]pentanedioic Acid; p-Nitrobenzoylglutamic Acid; L-Glutamic Acid, N-(p-nitrobenzoyl)-; N-(p-Nitrobenzoyl)-L-glutamic Acid; N4-(p-Nitrobenzoyl)-L-glutamic Acid; Glutamic Acid, N-(4-nitrobenzoyl)-
EINECS	Contact for details

Quality Control

Our n-(p-Nitrobenzoyl)Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and related substances. We adhere to cGMP principles where applicable to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which could affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.