Description

Cyclohexanecarbonitrile, 1-Chloro-2-Oxo- is a versatile nitrile derivative and a key chiral building block in advanced organic synthesis. Its value lies in its functionalized cyclohexane ring, which serves as a critical precursor for complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in the synthesis of fine chemicals and specialty intermediates. The CAS number for this product is 22518-23-6.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Ligand and Catalyst Development: Used in the research and preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Material Science Precursor: Potential use in the synthesis of monomers or additives for specialized polymers with unique properties.

Basic Information

Product Name	Cyclohexanecarbonitrile, 1-Chloro-2-Oxo-
CAS No.	22518-23-6
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	1-Chloro-2-oxocyclohexanecarbonitrile; 2-Oxo-1-chlorocyclohexanecarbonitrile; 1-Chloro-2-oxocyclohexane-1-carbonitrile; α-Chloro-α-cyanocyclohexanone; 2-Chloro-2-cyanocyclohexanone; Cyclohexanone, 2-chloro-2-cyano-; (Chlorocyanocyclohexyl) ketone
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarbonitrile, 1-Chloro-2-Oxo- is produced and tested under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) are provided with each shipment, documenting key parameters such as assay, identity, and specific impurities. We support custom synthesis and can tailor purity grades (including >99%) to meet specific project requirements under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive and should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.