Description

4,4-Difluorocyclohexanone is a versatile fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a ketone group flanked by fluorine atoms on a cyclohexane ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemicals: Acts as a monomer or modifier in the creation of high-performance polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis & Catalysis: A valuable substrate in academic and industrial research for exploring new fluorination reactions, asymmetric synthesis, and catalytic processes.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	4,4-Difluorocyclohexanone
CAS No.	22515-18-0
Molecular Formula	C6H8F2O
Molecular Weight	134.13 g/mol
Synonyms	4,4-Difluorocyclohexan-1-one; 1,1-Difluorocyclohexan-4-one; Cyclohexanone, 4,4-difluoro-; 4,4-Difluorocyclohexanone; 22515-18-0; 4,4-Difluoro-1-cyclohexanone
EINECS	Contact for details

Quality Control

Our 4,4-Difluorocyclohexanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.