Description

Ethyl 5,5-Difluoro-2-Oxo-Cyclohexanecarboxylate is a high-purity fluorinated cyclic keto ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the efficient construction of complex molecular architectures, particularly those requiring the introduction of fluorine atoms and reactive carbonyl handles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, including protease inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides with enhanced biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: An important reagent for introducing the difluoromethylene (CF2) group into complex molecules, leveraging the unique properties of fluorine.
• Specialty Chemical Production: Employed in the manufacture of performance chemicals, such as specialty polymers or liquid crystals, where fluorination alters physical properties.

Basic Information

Product Name	Ethyl 5,5-Difluoro-2-Oxo-Cyclohexanecarboxylate
CAS No.	22515-17-9
Molecular Formula	C9H12F2O3
Molecular Weight	206.19 g/mol
Synonyms	5,5-Difluoro-2-oxocyclohexanecarboxylic acid ethyl ester; Ethyl 5,5-difluoro-2-oxocyclohexanecarboxylate; 2-Oxo-5,5-difluorocyclohexanecarboxylic Acid Ethyl Ester; 5,5-Difluoro-2-oxo-cyclohexanecarboxylic acid ethyl ester; Cyclohexanecarboxylic acid, 5,5-difluoro-2-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5,5-Difluoro-2-Oxo-Cyclohexanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.