Description

3-Deoxy-3-Fluoro-1,2:5,6-Bis-o-(1-Methylethylidene)-α-D-Galactofuranose is a high-value, protected fluorinated sugar derivative, serving as a critical chiral building block in advanced organic synthesis. Its primary commercial value lies in enabling the precise introduction of fluorine into complex molecular architectures, a key strategy for modulating the biological activity and metabolic stability of target compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel nucleoside analogues, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated nucleoside analogues and antiviral/anticancer prodrugs.
• Glycochemistry Research: Used as a protected, fluorinated galactofuranose donor for studying carbohydrate-protein interactions and enzyme mechanisms.
• Agrochemical Synthesis: Serves as a chiral template for creating novel, fluorinated active ingredients with enhanced efficacy and environmental profile.
• Medicinal Chemistry Probe: Employed to investigate the role of fluorine substitution in drug metabolism, bioavailability, and receptor binding.
• Fluorine Chemistry: A valuable reagent for developing new fluorination methodologies and studying the stereoelectronic effects of the C-F bond.
• Diagnostic Agent Development: Potential use in the synthesis of fluorinated tracers and contrast agents for imaging technologies like PET (Positron Emission Tomography).

Basic Information

Product Name	3-Deoxy-3-Fluoro-1,2:5,6-Bis-o-(1-Methylethylidene)-α-D-Galactofuranose
CAS No.	22435-76-3
Molecular Formula	C₁₂H₁₉FO₅
Molecular Weight	262.27 g/mol
Synonyms	3-Deoxy-3-fluoro-1,2:5,6-di-O-isopropylidene-α-D-galactofuranose; 3-Fluoro-1,2:5,6-di-O-isopropylidene-α-D-galactofuranose; 3-Fluoro-1,2:5,6-di-O-(1-methylethylidene)-α-D-galactofuranose; 3-Fluoro-di-O-isopropylidene-α-D-galactofuranose; Fluorinated galactofuranose derivative; Protected 3-fluoro-galactose
EINECS	Contact for details

Quality Control

Our 3-Deoxy-3-Fluoro-1,2:5,6-Bis-o-(1-Methylethylidene)-α-D-Galactofuranose is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards required for research and process chemistry. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management systems, and specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials such as strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.