Description

1-Bromo-2,6-Dicyanobenzene is a high-value, multi-functional aromatic building block characterized by its bromine and nitrile substituents, enabling precise chemical transformations. This compound matters for its role as a versatile intermediate in the synthesis of complex organic molecules, particularly in advanced material science and pharmaceutical research. It is needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing novel heterocycles and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing complex heterocyclic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and cyano groups for structural diversification.
• Material Science: Serves as a monomer or building block for advanced polymers, liquid crystals, and organic electronic materials due to its rigid, functionalized benzene ring.
• Cross-Coupling Reactions: The bromine atom is an excellent site for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Nucleophilic Substitution & Transformation: The cyano groups can be hydrolyzed to carboxylic acids, reduced to amines, or used to form tetrazoles, expanding its utility in medicinal chemistry.
• Ligand & Catalyst Development: Used to synthesize specialized chelating ligands for metal catalysts used in asymmetric synthesis and industrial processes.

Basic Information

Product Name	1-Bromo-2,6-Dicyanobenzene
CAS No.	22433-90-5
Molecular Formula	C8H3BrN2
Molecular Weight	207.03 g/mol
Synonyms	2,6-Dicyanobenzene Bromide; 2-Bromo-1,3-dicyanobenzene; 3-Bromophthalonitrile; 1,3-Dicyano-2-bromobenzene; 2-Bromobenzene-1,3-dicarbonitrile; Bromo-dicyanobenzene; NSC 403107; Phthalonitrile, 3-bromo-
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,6-Dicyanobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.