Description

4,4-Difluorocyclohexanol is a versatile fluorinated cyclohexanol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms and the hydroxyl group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for creating novel herbicides and pesticides with enhanced metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Fluorinated component used to fine-tune the dielectric anisotropy and viscosity of liquid crystal mixtures for displays, and as a synthon for electron-transport materials.
• Polymer Modification: Monomer or modifier for introducing fluorine into polymer backbones to alter surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Used in various fluorination reactions, ring-opening transformations, and as a chiral pool starting material for asymmetric synthesis.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex fluorinated aromatic systems.

Basic Information

Product Name	4,4-Difluorocyclohexanol
CAS No.	22419-35-8
Molecular Formula	C6H10F2O
Molecular Weight	136.14 g/mol
Synonyms	4,4-Difluorocyclohexan-1-ol; trans-4,4-Difluorocyclohexanol; 1,4-Difluorocyclohexanol; 4,4-Difluoro-1-cyclohexanol; Cyclohexanol, 4,4-difluoro-; 4,4-Difluorocyclohexyl alcohol
EINECS	Contact for details

Quality Control

Our 4,4-Difluorocyclohexanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.