Description

1-(Piperidin-1-Yl)Propane-1,2-Dione (CAS NO 22381-22-2) is a specialized diketone derivative featuring a piperidine moiety, serving as a versatile building block in advanced organic synthesis. Its molecular structure makes it a valuable precursor for the development of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals.
• Academic and R&D: Serves as a critical reagent in medicinal chemistry research and method development laboratories.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers.

Basic Information

Product Name	1-(Piperidin-1-Yl)Propane-1,2-Dione
CAS No.	22381-22-2
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	1-Piperidin-1-ylpropane-1,2-dione; 1,2-Propanedione, 1-(1-piperidinyl)-; 1-Piperidinyl-1,2-propanedione; NSC 163045; 1-(1-Piperidinyl)-1,2-propanedione; 2-Oxopropionaldehyde piperidin-1-yl ketone; α-Oxopropionaldehyde N-piperidyl ketone
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-1-Yl)Propane-1,2-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support audits and custom validation protocols for cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.