Description

n-Acetyl-6-Methoxytryptamine is a high-purity synthetic indole derivative, structurally related to melatonin. This compound matters as a versatile and critical pharmaceutical intermediate and research chemical for developing new therapeutic agents and studying neurological pathways. It is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and academic research institutions focused on neurochemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel melatonin receptor agonists and related neuroactive compounds.
• Biochemical Research: Used as a reference standard and precursor in studies of serotonin and melatonin pathways, sleep-wake cycles, and circadian rhythm regulation.
• Neurological Disorder Research: Investigated for potential applications in developing treatments for insomnia, depression, and other mood disorders.
• Academic & Contract Research: Supplied to universities and CROs for basic science and preclinical studies requiring high-purity, well-characterized chemical entities.
• Process Development: Serves as a starting material for process chemistry teams optimizing scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Analytical Standard: Utilized in HPLC, LC-MS, and NMR as a certified reference material for method development and quality control in analytical laboratories.

Basic Information

Product Name	n-Acetyl-6-Methoxytryptamine
CAS No.	22375-73-1
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	6-Methoxy-N-acetyltryptamine; 6-Methoxymelatonin; 6-Methoxy-N-acetyl-5-hydroxytryptamine; 6-Methoxy-N-acetylserotonin; 6-Methoxy-N-acetyl-5-HT; 6-Methoxy-N-acetyl-5-hydroxytryptamine; N-Acetyl-6-methoxytryptamine; N-[2-(6-Methoxy-1H-indol-3-yl)ethyl]acetamide
EINECS	Contact for details

Quality Control

Our n-Acetyl-6-Methoxytryptamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.